Luca Mosca was born and raised in Milan. First, at the insistence of his family, Luca studied pharmacy but after completing his medical education, he pursued fashion.
Luca worked as a fashion designer at Zamasport, Italy’s top couture production company, which was creating collections for Helmut Lang, Gucci, Romeo Gigli, Norma Kamali, Katharine Hamnett, Costume National. 

In 1994, Luca Mosca moved to New York and after designing for American fashion companies, together with designer Marco Cattoretti he founded his own fashion brand LUCA+MARCO, a label very much in demand in the high end boutiques of Europe, Asia and America. In the mid-90’s Luca and Marco were offered to design the costumes of a small feature film and that opportunity started a long costume design career.

Currently, Luca Mosca is designing costumes for film and TV and acting in film and theater.